The labile nature of consolidation theory.

نویسندگان

  • K Nader
  • G E Schafe
  • J E LeDoux
چکیده

'Consolidation' has been used to describe distinct but related processes. In considering the implications of our recent findings on the lability of reactivated fear memories, we view consolidation and reconsolidation in terms of molecular events taking place within neurons as opposed to interactions between brain regions. Our findings open up a new dimension in the study of memory consolidation. We argue that consolidation is not a one-time event, but instead is reiterated with subsequent activation of the memories.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Exploring a Family Consolidation Model based on the Lazarus Multifaceted Theory among Couples in Yazd City(Qualitative)

Family consolidation leads the society towards its desirable ideals. Therefore, the youth should be encouraged to marry and provided with the necessary trainings on family consolidation. The present qualitative research aimed to develop a family consolidation model based on the Lazarus Multifaceted Model in order to consolidate the family foundation. To collect the study information, 19 famil...

متن کامل

Obstacles to the Consolidation of Democracy in Turkey (2002 –present) "The vague political nature, the organized structure of the party, and the authoritarian leadership"

Abstract The process of democratization of Turkey over more than a century has been accompanied by various barriers, such as military intervention, inefficient and passive opposition, undemocratic performance and sponsor of the religious-political tariqa, ethnic and religious rifts, authoritarian government leaders, political parties’ poor and sometimes biased performance, contradictory intern...

متن کامل

Linking New Information to a Reactivated Memory Requires Consolidation and Not Reconsolidation Mechanisms

A new memory is initially labile and becomes stabilized through a process of consolidation, which depends on gene expression. Stable memories, however, can again become labile if reactivated by recall and require another phase of protein synthesis in order to be maintained. This process is known as reconsolidation. The functional significance of the labile phase of reconsolidation is unknown; o...

متن کامل

The neurobiology of consolidations, or, how stable is the engram?

Consolidation is the progressive postacquisition stabilization of long-term memory. The term is commonly used to refer to two types of processes: synaptic consolidation, which is accomplished within the first minutes to hours after learning and occurs in all memory systems studied so far; and system consolidation, which takes much longer, and in which memories that are initially dependent upon ...

متن کامل

The Role of Reconsolidation and the Dynamic Process of Long-Term Memory Formation and Storage

It is becoming increasingly clear that the processes of memory formation and storage are exquisitely dynamic. Elucidating the nature and temporal evolution of the biological changes that accompany encoding, storage, and retrieval is key to understand memory formation. For explicit or medial temporal lobe-dependent memories that form after a discrete event and are stored for a long time, the phy...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Nature reviews. Neuroscience

دوره 1 3  شماره 

صفحات  -

تاریخ انتشار 2000